NLRP4 drives olaparib resistance in pancreatic cancer
Olaparib has been approved as a treatment for metastatic pancreatic ductal adenocarcinoma in patients with BRCA1 (BRCA1 DNA repair associated) or BRCA2 mutations. However, a large portion of pancreatic cancer patients either exhibit inherent resistance or develop resistance over time. Understanding...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
|
Series: | Autophagy Reports |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/27694127.2024.2422729 |