Complete mapping of substrate translocation highlights the role of LeuT N-terminal segment in regulating transport cycle.

Neurotransmitter: sodium symporters (NSSs) regulate neuronal signal transmission by clearing excess neurotransmitters from the synapse, assisted by the co-transport of sodium ions. Extensive structural data have been collected in recent years for several members of the NSS family, which opened the w...

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Bibliographic Details
Main Authors: Mary Hongying Cheng, Ivet Bahar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4191883?pdf=render