Spatially Self‐Organized Three‐Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development

Spatially Self‐Organized Three‐Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development

Abstract Although human pluripotent stem cell (PSC)‐derived brain organoids have enabled researchers to gain insight into human brain development and disease, these organoids contain solely ectodermal cells and are not vascularized as occurs during brain development. Here it is created less complex...

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Bibliographic Details
Main Authors: Yoke Chin Chai, San Kit To, Susan Simorgh, Samantha Zaunz, YingLi Zhu, Karan Ahuja, Alix Lemaitre, Roya Ramezankhani, Bernard K. van derVeer, Keimpe Wierda, Stefaan Verhulst, Leo A. vanGrunsven, Vincent Pasque, Catherine Verfaillie
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
blood‐brain barrier
brain organoids
neurovascular
vascularization
Online Access:https://doi.org/10.1002/advs.202304421

Internet

https://doi.org/10.1002/advs.202304421

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