TREM2‐IGF1 Mediated Glucometabolic Enhancement Underlies Microglial Neuroprotective Properties During Ischemic Stroke

TREM2‐IGF1 Mediated Glucometabolic Enhancement Underlies Microglial Neuroprotective Properties During Ischemic Stroke

Abstract Microglia, the major resident immune cells in the central nervous system, serve as the frontline soldiers against cerebral ischemic injuries, possibly along with metabolic alterations. However, signaling pathways involved in the regulation of microglial immunometabolism in ischemic stroke r...

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Bibliographic Details
Main Authors: Sheng Yang, Chuan Qin, Man Chen, Yun‐Hui Chu, Yue Tang, Luo‐Qi Zhou, Hang Zhang, Ming‐Hao Dong, Xiao‐Wei Pang, Lian Chen, Long‐Jun Wu, Dai‐Shi Tian, Wei Wang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
ischemic stroke
microglia
oxidative phosphorylation
Trem2‐Igf1 signaling pathway
Online Access:https://doi.org/10.1002/advs.202305614

Internet

https://doi.org/10.1002/advs.202305614

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