Genetic polymorphisms of CYP2C19 in ecuadorian population: An interethnic approach

Genetic polymorphisms of CYP2C19 in ecuadorian population: An interethnic approach

Introduction: CYP2C19 is a highly polymorphic gene responsible for metabolizing commonly used drugs. CYP2C19*2,*3 (loss of activity alleles) and *17 (increased activity allele) are the principal alleles included in clinical guidelines, however their prevalence varies among different ethnicities. Ecu...

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Bibliographic Details
Main Authors: Alba Alonso Llorente, Josefa Salgado Garrido, Óscar Teijido Hermida, Fabricio González Andrade, Alberto Valiente Martín, Ana Julia Fanlo Villacampa, Jorge Vicente Romero
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
CYP2C19
Pharmacogenetics
Ecuador
Kichwa
Afrodescendants
Mestizos
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024045973

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http://www.sciencedirect.com/science/article/pii/S2405844024045973

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