Preparation and Clinical Translation Study of 99mTc-labeled Prostate-Specific Membrane Antigen Inhibitor HYNIC-P137

To develop a low bladder accumulation SPECT prostate cancer imaging agent, 99mTc-P137 was prepared on the basis of 68Ga-P137 structure, and the probe was subjected to detailed preclinical evaluation and preliminary clinical translation studies. The labeled precursor HYNIC-P137 was prepared by solid-...

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Bibliographic Details
Main Author: DUAN Xiaojiang;LIAO Xuhe;XIAO Di;ZHANG Zhuochen;ZHANG Junbo;FAN Yan;YANG Xing
Format: Article
Language:zho
Published: Editorial Board of Journal of Isotopes 2023-08-01
Series:Journal of Isotopes
Subjects:
Online Access:http://www.tws.org.cn/CN/10.7538/tws.2023.36.04.0389