Genomewide Identification of Essential Genes and Fitness Determinants of <named-content content-type="genus-species">Streptococcus mutans</named-content> UA159

Genomewide Identification of Essential Genes and Fitness Determinants of <named-content content-type="genus-species">Streptococcus mutans</named-content> UA159

ABSTRACT Transposon mutagenesis coupled with next-generation DNA sequencing (Tn-seq) is a powerful tool for discovering regions of the genome that are required for the survival of bacteria in different environments. We adapted this technique to the dental caries pathogen Streptococcus mutans UA159 a...

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Bibliographic Details
Main Authors: Robert C. Shields, Lin Zeng, David J. Culp, Robert A. Burne
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mSphere
Subjects:
Streptococcus
antimicrobial targets
dental caries
essential genome
transposon sequencing
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00031-18

Internet

https://journals.asm.org/doi/10.1128/mSphere.00031-18

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