Oxidative stress is intrinsic to staphylococcal adaptation to fatty acid synthesis antibiotics

Oxidative stress is intrinsic to staphylococcal adaptation to fatty acid synthesis antibiotics

Summary: Antibiotics inhibiting the fatty acid synthesis pathway (FASII) of the major pathogen Staphylococcus aureus reach their enzyme targets, but bacteria continue growth by using environmental fatty acids (eFAs) to produce phospholipids. We assessed the consequences and effectors of FASII-antibi...

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Bibliographic Details
Main Authors: Paprapach Wongdontree, Aaron Millan-Oropeza, Jennifer Upfold, Jean-Pierre Lavergne, David Halpern, Clara Lambert, Adeline Page, Gérald Kénanian, Christophe Grangeasse, Céline Henry, Agnès Fouet, Karine Gloux, Jamila Anba-Mondoloni, Alexandra Gruss
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Microbiology
Microbial metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224007260

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224007260

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