ISG15 mediates the function of extracellular vesicles in promoting ovarian cancer progression and metastasis

ISG15 mediates the function of extracellular vesicles in promoting ovarian cancer progression and metastasis

Abstract The interferon stimulated gene 15 (ISG15), a ubiquitin like protein and its conjugates have been implicated in various human malignancies. However, its role in ovarian cancer progression and metastasis is largely unknown. In high grade serous ovarian cancer (HGSOC), ascites is the major con...

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Bibliographic Details
Main Authors: Kalpana Deepa Priya Dorayappan, Vincent Wagner, Dongju Park, Meghan M. Newcomer, Michelle D. S. Lightfoot, Deepika Kalaiyarasan, Takahiko Sakaue, Wafa Khadraoui, Lianbo Yu, Qi‐En Wang, G. Larry Maxwell, David O'Malley, Raphael E. Pollock, David E. Cohn, Karuppaiyah Selvendiran
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Journal of Extracellular Biology
Subjects:
ascites
extracellular vesicles
ISG15
ISGylation
metastasis and biomarker
ovarian cancer
Online Access:https://doi.org/10.1002/jex2.92

Internet

https://doi.org/10.1002/jex2.92

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