Gene Networks Based on the Graphical Gaussian Model

This protocol describes how to build a gene network based on the graphical Gaussian model (GGM) from large scale microarray data. GGM uses partial correlation coefficient (pcor) to infer co-expression relationship between genes. Compared to the traditional Pearson’ correlation coefficient, partial c...

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Bibliographic Details
Main Author: Shisong Ma
Format: Article
Language:English
Published: Bio-protocol LLC 2012-02-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=119&type=0