Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance

Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance

ABSTRACT Five blaCTX-M-14-positive Klebsiella pneumoniae isolates (KpWEA1, KpWEA2, KpWEA3, KpWEA4-1, and KpWEA4-2) were consecutively obtained from a patient with relapsed acute myeloid leukemia who was continuously administered antimicrobials. Compared with KpWEA1 and KpWEA2, KpWEA3 showed decrease...

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Bibliographic Details
Main Authors: Mai Yoshino, Masamune Aihara, Yasuhiro Gotoh, Masaru Akimoto, Wakana Tatsuhara, Makiko Kiyosuke, Yuichi Matsushima, Takeshi Uchiumi, Tetsuya Hayashi, Dongchon Kang
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mSphere
Subjects:
Klebsiella
carbapenems
drug resistance evolution
multidrug resistance
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00734-21

Internet

https://journals.asm.org/doi/10.1128/mSphere.00734-21

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