Downregulation of Cavin‐1 Expression via Increasing Caveolin‐1 Degradation Prompts the Proliferation and Migration of Vascular Smooth Muscle Cells in Balloon Injury–Induced Neointimal Hyperplasia

Downregulation of Cavin‐1 Expression via Increasing Caveolin‐1 Degradation Prompts the Proliferation and Migration of Vascular Smooth Muscle Cells in Balloon Injury–Induced Neointimal Hyperplasia

BackgroundPercutaneous coronary intervention has been widely used in the treatment of ischemic heart disease, but vascular restenosis is a main limitation of percutaneous coronary intervention. Our previous work reported that caveolin‐1 had a key functional role in intimal hyperplasia, whereas wheth...

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Bibliographic Details
Main Authors: Li‐Jun Zhou, Xue‐Ying Chen, Shui‐Ping Liu, Lin‐Lin Zhang, Ya‐Nan Xu, Pan‐Wei Mu, Deng‐Feng Geng, Zhi Tan
Format: Article
Language:English
Published: Wiley 2017-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
caveolin‐1
Cavin‐1
migration
neointimal hyperplasia
polymerase I and transcript release factor
proliferation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.005754

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.005754

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