Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways

Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways

Abstract Peri-hilar cholangiocarcinoma (pCCA) is chemorefractory and limited genomic analyses have been undertaken in Western idiopathic disease. We undertook comprehensive genomic analyses of a U.K. idiopathic pCCA cohort to characterize its mutational profile and identify new targets. Whole exome...

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Bibliographic Details
Main Authors: Leonard M. Quinn, Sam Haldenby, Philip Antzcak, Anna Fowler, Katie Bullock, John Kenny, Timothy Gilbert, Timothy Andrews, Rafael Diaz-Nieto, Stephen Fenwick, Robert Jones, Eithne Costello-Goldring, Graeme Poston, William Greenhalf, Daniel Palmer, Hassan Malik, Chris Goldring
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33096-0

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https://doi.org/10.1038/s41598-023-33096-0

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