Spatial and temporal heterogeneity of tumor immune microenvironment between primary tumor and brain metastases in NSCLC

Abstract Background Brain metastasis is a common outcome in non-small cell lung cancer, and despite aggressive treatment, its clinical outcome is still frustrating. In recent years, immunotherapy has been developing rapidly, however, its therapeutic outcomes for primary lung cancer and brain metasta...

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Bibliographic Details
Main Authors: Jin-Sheng Liu, Yu-Xiang Cai, Yong-Ze He, Jian Xu, Su-Fang Tian, Zhi-Qiang Li
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-024-11875-w