Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex

Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex

Abstract The ventromedial prefrontal cortex (vmPFC; rodent infralimbic cortex (IL)), is posited to be an important locus of fear extinction-facilitating effects of the dopamine (DA) bio-precursor, L-DOPA, but this hypothesis remains to be formally tested. Here, in a model of impaired fear extinction...

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Bibliographic Details
Main Authors: Simone B. Sartori, Thomas M. V. Keil, Kai K. Kummer, Conor P. Murphy, Ozge Gunduz-Cinar, Michaela Kress, Karl Ebner, Andrew Holmes, Nicolas Singewald
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02708-8

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https://doi.org/10.1038/s41398-023-02708-8

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