Hepatic Peroxisome Proliferator-Activated Receptor Alpha Dysfunction in Porcine Septic Shock

Hepatic Peroxisome Proliferator-Activated Receptor Alpha Dysfunction in Porcine Septic Shock

Despite decades of research, sepsis remains one of the most urgent unmet medical needs. Mechanistic investigations into sepsis have mainly focused on targeting inflammatory pathways; however, recent data indicate that sepsis should also be seen as a metabolic disease. Targeting metabolic dysregulati...

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Bibliographic Details
Main Authors: Jolien Vandewalle, Bruno Garcia, Steven Timmermans, Tineke Vanderhaeghen, Lise Van Wyngene, Melanie Eggermont, Hester Dufoor, Céline Van Dender, Fëllanza Halimi, Siska Croubels, Antoine Herpain, Claude Libert
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
sepsis
swine
metabolism
PPARɑ
free fatty acids
Online Access:https://www.mdpi.com/2073-4409/11/24/4080

Internet

https://www.mdpi.com/2073-4409/11/24/4080

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