CD8+ T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production

CD8+ T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production

Abstract Whether CD8+ T lymphocytes control human immunodeficiency virus infection by cytopathic or non-cytopathic mechanisms is not fully understood. Multiple studies highlighted non-cytopathic effects, but one hypothesis is that cytopathic effects of CD8+ T cells occur before viral production. Her...

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Bibliographic Details
Main Authors: Benjamin B. Policicchio, Erwing Fabian Cardozo-Ojeda, Cuiling Xu, Dongzhu Ma, Tianyu He, Kevin D. Raehtz, Ranjit Sivanandham, Adam J. Kleinman, Alan S. Perelson, Cristian Apetrei, Ivona Pandrea, Ruy M. Ribeiro
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42435-8

Internet

https://doi.org/10.1038/s41467-023-42435-8

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