Immunodominant Linear B-Cell Epitopes of SARS-CoV-2 Spike, Identified by Sera from K18-hACE2 Mice Infected with the WT or Variant Viruses

Immunodominant Linear B-Cell Epitopes of SARS-CoV-2 Spike, Identified by Sera from K18-hACE2 Mice Infected with the WT or Variant Viruses

SARS-CoV-2 surface spike protein mediates the viral entry into the host cell and represents the primary immunological target of COVID-19 vaccines as well as post-exposure immunotherapy. Establishment of the highly immunogenic B-cell epitope profile of SARS-CoV-2 proteins in general, and that of the...

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Bibliographic Details
Main Authors: Yinon Levy, Ron Alcalay, Anat Zvi, Efi Makdasi, Eldar Peretz, Tal Noy-Porat, Theodor Chitlaru, Michal Mandelboim, Ohad Mazor, Ronit Rosenfeld
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Vaccines
Subjects:
COVID-19
SARS-CoV-2
epitope mapping
linear epitopes
K18-hACE2
Online Access:https://www.mdpi.com/2076-393X/10/2/251

Internet

https://www.mdpi.com/2076-393X/10/2/251

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