The Introduction of Detergents in Thermal Proteome Profiling Requires Lowering the Applied Temperatures for Efficient Target Protein Identification

The Introduction of Detergents in Thermal Proteome Profiling Requires Lowering the Applied Temperatures for Efficient Target Protein Identification

Although the use of detergents in thermal proteome profiling (TPP) has become a common practice to identify membrane protein targets in complex biological samples, surprisingly, there is no proteome-wide investigation into the impacts of detergent introduction on the target identification performanc...

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Bibliographic Details
Main Authors: Yuying Ye, Kejia Li, Yanni Ma, Xiaolei Zhang, Yanan Li, Ting Yu, Yan Wang, Mingliang Ye
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
mild detergents
thermal proteome profiling
target protein identification
Online Access:https://www.mdpi.com/1420-3049/28/12/4859

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https://www.mdpi.com/1420-3049/28/12/4859

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