The Introduction of Detergents in Thermal Proteome Profiling Requires Lowering the Applied Temperatures for Efficient Target Protein Identification

Although the use of detergents in thermal proteome profiling (TPP) has become a common practice to identify membrane protein targets in complex biological samples, surprisingly, there is no proteome-wide investigation into the impacts of detergent introduction on the target identification performanc...

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Bibliographic Details
Main Authors: Yuying Ye, Kejia Li, Yanni Ma, Xiaolei Zhang, Yanan Li, Ting Yu, Yan Wang, Mingliang Ye
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/12/4859

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