The lipooligosaccharide of the gut symbiont Akkermansia muciniphila exhibits a remarkable structure and TLR signaling capacity

The lipooligosaccharide of the gut symbiont Akkermansia muciniphila exhibits a remarkable structure and TLR signaling capacity

Abstract The cell-envelope of Gram-negative bacteria contains endotoxic lipopolysaccharides (LPS) that are recognized by the innate immune system via Toll-Like Receptors (TLRs). The intestinal mucosal symbiont Akkermansia muciniphila is known to confer beneficial effects on the host and has a Gram-n...

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Bibliographic Details
Main Authors: Pilar Garcia-Vello, Hanne L. P. Tytgat, Janneke Elzinga, Matthias Van Hul, Hubert Plovier, Marta Tiemblo-Martin, Patrice D. Cani, Simone Nicolardi, Marco Fragai, Cristina De Castro, Flaviana Di Lorenzo, Alba Silipo, Antonio Molinaro, Willem M. de Vos
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52683-x

Internet

https://doi.org/10.1038/s41467-024-52683-x

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