A genetically encoded tool kit for manipulating and monitoring membrane phosphatidylinositol 4,5-bisphosphate in intact cells.

A genetically encoded tool kit for manipulating and monitoring membrane phosphatidylinositol 4,5-bisphosphate in intact cells.

Most ion channels are regulated by phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)) in the cell membrane by diverse mechanisms. Important molecular tools to study ion channel regulation by PtdIns(4,5)P(2) in living cells have been developed in the past. These include fluorescent PH-domains as...

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Bibliographic Details
Main Authors: Fabian Hertel, Agathe Switalski, Elisa Mintert-Jancke, Katharina Karavassilidou, Kirsten Bender, Lutz Pott, Marie-Cécile Kienitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3111442?pdf=render

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http://europepmc.org/articles/PMC3111442?pdf=render

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