Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii.

Innate immunity is the first line of defense against microbial insult. The transcription factor, IRF3, is needed by mammalian cells to mount innate immune responses against many microbes, especially viruses. IRF3 remains inactive in the cytoplasm of uninfected cells; upon virus infection, it gets ph...

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Váldodahkkit: Tanmay Majumdar, Saurabh Chattopadhyay, Evgeny Ozhegov, Jayeeta Dhar, Ramansu Goswami, Ganes C Sen, Sailen Barik
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Public Library of Science (PLoS) 2015-03-01
Ráidu:PLoS Pathogens
Liŋkkat:http://europepmc.org/articles/PMC4374777?pdf=render