EV-Mediated Chemoresistance in the Tumor Microenvironment: Is NF-κB a Player?

Drug resistance is a major impediment to patient survival and remains the primary cause of unsuccessful cancer therapy. Drug resistance occurs in many tumors and is frequently induced by chemotherapy which triggers a defensive response both in cancerous and cancer-associated cells that constitute th...

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Bibliographic Details
Main Authors: Mauro Di Vito Nolfi, Davide Vecchiotti, Irene Flati, Daniela Verzella, Monica Di Padova, Edoardo Alesse, Daria Capece, Francesca Zazzeroni
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.933922/full