How imputation can mitigate SNP ascertainment Bias

How imputation can mitigate SNP ascertainment Bias

Abstract Background Population genetic studies based on genotyped single nucleotide polymorphisms (SNPs) are influenced by a non-random selection of the SNPs included in the used genotyping arrays. The resulting bias in the estimation of allele frequency spectra and population genetics parameters li...

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Bibliographic Details
Main Authors: Johannes Geibel, Christian Reimer, Torsten Pook, Steffen Weigend, Annett Weigend, Henner Simianer
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Genomics
Subjects:
SNP ascertainment bias
Imputation
Chickens
Population genetics
Online Access:https://doi.org/10.1186/s12864-021-07663-6

Internet

https://doi.org/10.1186/s12864-021-07663-6

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