An Oxidative Stress-Related Gene Pair (CCNB1/PKD1), Competitive Endogenous RNAs, and Immune-Infiltration Patterns Potentially Regulate Intervertebral Disc Degeneration Development

An Oxidative Stress-Related Gene Pair (CCNB1/PKD1), Competitive Endogenous RNAs, and Immune-Infiltration Patterns Potentially Regulate Intervertebral Disc Degeneration Development

Oxidative stress (OS) irreversibly affects the pathogenesis of intervertebral disc degeneration (IDD). Certain non-coding RNAs act as competitive endogenous RNAs (ceRNAs) that regulate IDD progression. Analyzing the signatures of oxidative stress-related gene (OSRG) pairs and regulatory ceRNA mechan...

Full description

Bibliographic Details
Main Authors: Shuai Cao, Hao Liu, Jiaxin Fan, Kai Yang, Baohui Yang, Jie Wang, Jie Li, Liesu Meng, Haopeng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
intervertebral disc degeneration
oxidative stress
gene pair
immune infiltration
competitive endogenous RNA
differential expression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.765382/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.765382/full

Similar Items