Critical role of Rho proteins in myosin light chain di-phosphorylation during early phase of endothelial barrier disruption
Abstract We previously reported the Rho-associated coiled-coil containing protein kinase (ROCK)-mediated di-phosphorylation of myosin light chain (MLC) and actin bundle formation at the cell periphery as early events of the endothelial barrier disruption. We herein examined the role of RhoA during e...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Journal of Physiological Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12576-022-00857-x |