Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

Abstract Background Cerebrovascular disease (CVD) and amyloid-β (Aβ) often coexist, but their influence on neurodegeneration and cognition in predementia stages remains unclear. We investigated the association between CVD and Aβ on neurodegenerative markers and cognition in patients without dementia...

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Main Authors: Isabelle Bos, Frans R. Verhey, Inez H.G.B. Ramakers, Heidi I. L. Jacobs, Hilkka Soininen, Yvonne Freund-Levi, Harald Hampel, Magda Tsolaki, Åsa K. Wallin, Mark A. van Buchem, Ania Oleksik, Marcel M. Verbeek, Marcel Olde Rikkert, Wiesje M. van der Flier, Philip Scheltens, Pauline Aalten, Pieter Jelle Visser, Stephanie J. B. Vos
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13195-017-0328-9