Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia

Abstract Our previous study has announced that phosphorylated microtubule-associated protein 4 (p-MAP4) accelerated keratinocytes migration and proliferation under hypoxia through depolymerizing microtubules. However, p-MAP4 should exhibit inhibitory effects on wound healing, for it also impaired mi...

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Bibliographic Details
Main Authors: Yanhai Feng, Lingfei Li, Qiong Zhang, Yongqing He, Yao Huang, Junhui Zhang, Dongxia Zhang, Yuesheng Huang, Xia Lei, Jiongyu Hu, Gaoxing Luo
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01465-3