Development and characterization of a panel of anti-idiotype antibodies to 1C10 that cross-neutralize HIV-1 subtype B viruses

The V3 loop of the human immunodeficiency virus type 1 (HIV-1) envelope protein (Env) is one of the conserved immunogenic regions targeted by neutralizing antibodies (nAb). Two different binding modes of anti-V3 abs have been reported in studies using two V3 mimotopes: the ladle-type and cradle-type...

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Bibliographic Details
Main Authors: Yu Kaku, Kaho Matsumoto, Takeo Kuwata, Hasan Md Zahid, Shashwata Biswas, Miroslaw K. Gorny, Shuzo Matsushita
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Virology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.932187/full