The Epigenetic Regulation of Microenvironment in Hepatocellular Carcinoma

The Epigenetic Regulation of Microenvironment in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a highly lethal and complex malignancy strongly influenced by the surrounding tumor microenvironment. The HCC microenvironment comprises hepatic stellate cells (HSCs), tumor-associated macrophages (TAMs), stromal and endothelial cells, and the underlying extracellul...

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Bibliographic Details
Main Authors: Fang Wang, Greg Malnassy, Wei Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
tumor microenvironment
DNA methylation
histone methyltransferases
histone deacetylases
microRNAs
hepatic stellate cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.653037/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.653037/full

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