Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells.

Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells.

The major obstacle of successful tumor treatment with carboplatin (CBP) is the development of drug resistance. In the present study, we found that following treatment with CBP the amount of platinum which enters the human laryngeal carcinoma (HEp2)-derived CBP-resistant (7T) cells is reduced relativ...

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Bibliographic Details
Main Authors: Anamaria Brozovic, Lidija Vuković, Darija Stupin Polančac, Istvan Arany, Beate Köberle, Gerhard Fritz, Zeljka Fiket, Dragomira Majhen, Andreja Ambriović-Ristov, Maja Osmak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781097?pdf=render

Internet

http://europepmc.org/articles/PMC3781097?pdf=render

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