Study of Ubiquitin Pathway Genes in a French Population with Amyotrophic Lateral Sclerosis: Focus on <i>HECW1</i> Encoding the E3 Ligase NEDL1

Study of Ubiquitin Pathway Genes in a French Population with Amyotrophic Lateral Sclerosis: Focus on <i>HECW1</i> Encoding the E3 Ligase NEDL1

The ubiquitin pathway, one of the main actors regulating cell signaling processes and cellular protein homeostasis, is directly involved in the pathophysiology of amyotrophic lateral sclerosis (ALS). We first analyzed, by a next-generation sequencing (NGS) strategy, a series of genes of the ubiquiti...

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Bibliographic Details
Main Authors: Shanez Haouari, Christian Robert Andres, Debora Lanznaster, Sylviane Marouillat, Céline Brulard, Audrey Dangoumau, Devina Ung, Charlotte Veyrat-Durebex, Frédéric Laumonnier, Hélène Blasco, Philippe Couratier, Philippe Corcia, Patrick Vourc’h
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
amyotrophic lateral sclerosis
genetic
ALS
ubiquitin
<i>HECW1</i>
Online Access:https://www.mdpi.com/1422-0067/24/2/1268

Internet

https://www.mdpi.com/1422-0067/24/2/1268

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