Integrated analysis of lncRNA, miRNA and mRNA profiles reveals potential lncRNA functions during early HIV infection

Integrated analysis of lncRNA, miRNA and mRNA profiles reveals potential lncRNA functions during early HIV infection

Abstract Background Long noncoding RNAs (lncRNAs) can regulate gene expression in a cis-regulatory fashion or as “microRNA sponges”. However, the expression and functions of lncRNAs during early human immunodeficiency virus (HIV) infection (EHI) remain unclear. Methods 3 HAART-naive EHI patients and...

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Bibliographic Details
Main Authors: Lianwei Ma, Hui Zhang, Yue Zhang, Hailong Li, Minghui An, Bin Zhao, Haibo Ding, Junjie Xu, Hong Shang, Xiaoxu Han
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Translational Medicine
Subjects:
HIV-1
lncRNA
mRNA
miRNA
Cis-regulatory
ceRNA
Online Access:https://doi.org/10.1186/s12967-021-02802-9

Internet

https://doi.org/10.1186/s12967-021-02802-9

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