Gene expression profiling during early acute febrile stage of dengue infection can predict the disease outcome.

We report the detailed development of biomarkers to predict the clinical outcome under dengue infection. Transcriptional signatures from purified peripheral blood mononuclear cells were derived from whole-genome gene-expression microarray data, validated by quantitative PCR and tested in independent...

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Bibliographic Details
Main Authors: Eduardo J M Nascimento, Ulisses Braga-Neto, Carlos E Calzavara-Silva, Ana L V Gomes, Frederico G C Abath, Carlos A A Brito, Marli T Cordeiro, Ana M Silva, Cecilia Magalhães, Raoni Andrade, Laura H V G Gil, Ernesto T A Marques
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2775946?pdf=render