Synthesis of Benzofuran Derivatives via a DMAP-Mediated Tandem Cyclization Reaction Involving <i>ortho</i>-Hydroxy α-Aminosulfones
An efficient cascade cyclization strategy was developed to synthesize aminobenzofuran spiroindanone and spirobarbituric acid derivatives utilizing 2-bromo-1,3-indandione, 5-bromo-1,3-dimethylbarbituric acid, and <i>ortho</i>-hydroxy α-aminosulfones as substrates. Under the optimized reac...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-08-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/29/16/3725 |