Synthesis of Benzofuran Derivatives via a DMAP-Mediated Tandem Cyclization Reaction Involving <i>ortho</i>-Hydroxy α-Aminosulfones

Synthesis of Benzofuran Derivatives via a DMAP-Mediated Tandem Cyclization Reaction Involving <i>ortho</i>-Hydroxy α-Aminosulfones

An efficient cascade cyclization strategy was developed to synthesize aminobenzofuran spiroindanone and spirobarbituric acid derivatives utilizing 2-bromo-1,3-indandione, 5-bromo-1,3-dimethylbarbituric acid, and <i>ortho</i>-hydroxy α-aminosulfones as substrates. Under the optimized reac...

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Những tác giả chính: Rong-Rong Zhu, Xi-Qiang Hou, Da-Ming Du
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: MDPI AG 2024-08-01
Loạt:Molecules
Những chủ đề:
benzofuran
<i>ortho</i>-hydroxy α-amino sulfones
tandem cyclization reaction
spirocyclic compounds
Mannich reaction
Truy cập trực tuyến:https://www.mdpi.com/1420-3049/29/16/3725

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https://www.mdpi.com/1420-3049/29/16/3725

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