HDAC inhibitors: Targets for tumor therapy, immune modulation and lung diseases

HDAC inhibitors: Targets for tumor therapy, immune modulation and lung diseases

Histone deacetylases (HDACs) are enzymes that play a key role in the epigenetic regulation of gene expression by remodeling chromatin. Inhibition of HDACs is a prospective therapeutic approach for reversing epigenetic alteration in several diseases. In preclinical research, numerous types of HDAC in...

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Bibliographic Details
Main Authors: Geetha Shanmugam, Sudeshna Rakshit, Koustav Sarkar
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Translational Oncology
Subjects:
Histone deacetylases
HDAC inhibitors
Epigenetic regulation
Lung cancer
Chronic obstructive pulmonary disease
Nanocarrier-mediated HDAC inhibitor delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332100303X

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http://www.sciencedirect.com/science/article/pii/S193652332100303X

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