The Interaction of EphA4 With PDGFRβ Regulates Proliferation and Neuronal Differentiation of Neural Progenitor Cells in vitro and Promotes Neurogenesis in vivo

The Interaction of EphA4 With PDGFRβ Regulates Proliferation and Neuronal Differentiation of Neural Progenitor Cells in vitro and Promotes Neurogenesis in vivo

Neural progenitor cells (NPCs) have great potentials in cell replacement therapy for neurodegenerative diseases, such as Alzheimer’s disease (AD), by promoting neurogenesis associated with hippocampal memory improvement. Ephrin receptors and angiogenic growth factor receptors have a marked impact on...

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Bibliographic Details
Main Authors: Qingfa Chen, Hao Song, Chuanguo Liu, Jun Xu, Chuanfei Wei, Wei Wang, Fabin Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
ephrin receptor A4
platelet-derived growth factor receptor β
neural progenitor cell
differentiation
hippocampal neurogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00007/full

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https://www.frontiersin.org/article/10.3389/fnagi.2020.00007/full

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