Minilungs from Human Embryonic Stem Cells to Study the Interaction of Streptococcus pneumoniae with the Respiratory Tract

ABSTRACT The new generation of organoids derived from human pluripotent stem cells holds a promising strategy for modeling host-bacteria interaction studies. Organoids recapitulate the composition, diversity of cell types, and, to some extent, the functional features of the native organ. We generate...

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Main Authors: Julio Sempere, Suélen Andreia Rossi, Irene Chamorro-Herrero, Fernando González-Camacho, María Pilar de Lucas, José María Rojas-Cabañeros, Carlos Pelleschi Taborda, Óscar Zaragoza, José Yuste, Alberto Zambrano
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00453-22