TNF blockade contributes to restore lipid oxidation during exercise in children with juvenile idiopathic arthritis

TNF blockade contributes to restore lipid oxidation during exercise in children with juvenile idiopathic arthritis

Abstract Background Children with juvenile idiopathic arthritis (JIA) have impaired physical abilities. TNF-α plays a crucial role in this pathogenesis, but it is also involved in the use of lipids and muscle health. Objective of this study was to explore substrate oxidation and impact of TNF blocka...

Full description

Bibliographic Details
Main Authors: Emmanuelle Rochette, Pierre Bourdier, Bruno Pereira, Eric Doré, Anthony Birat, Sébastien Ratel, Stéphane Echaubard, Pascale Duché, Etienne Merlin
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Pediatric
Physical activity
Inflammation
Fat oxidation
Metabolism
Online Access:http://link.springer.com/article/10.1186/s12969-019-0354-1

Internet

http://link.springer.com/article/10.1186/s12969-019-0354-1

Similar Items