Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

The skin lesion erythema migrans (EM) is an initial sign of the Ixodes tick–transmitted Borreliella spirochetal infection known as Lyme disease. T cells and innate immune cells have previously been shown to predominate the EM lesion and promote the reaction. Despite the established importance of B c...

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Bibliographic Details
Main Authors: Ruoyi Jiang, Hailong Meng, Khadir Raddassi, Ira Fleming, Kenneth B. Hoehn, Kenneth R. Dardick, Alexia A. Belperron, Ruth R. Montgomery, Alex K. Shalek, David A. Hafler, Steven H. Kleinstein, Linda K. Bockenstedt
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-06-01
Series:JCI Insight
Subjects:
Immunology
Infectious disease
Online Access:https://doi.org/10.1172/jci.insight.148035

Internet

https://doi.org/10.1172/jci.insight.148035

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