Sevoflurane Effects on Neuronal Energy Metabolism Correlate with Activity States While Mitochondrial Function Remains Intact

Sevoflurane Effects on Neuronal Energy Metabolism Correlate with Activity States While Mitochondrial Function Remains Intact

During general anesthesia, alterations in neuronal metabolism may induce neurotoxicity and/or neuroprotection depending on the dose and type of the applied anesthetic. In this study, we investigate the effects of clinically relevant concentrations of sevoflurane (2% and 4%, i.e., 1 and 2 MAC) on dif...

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Bibliographic Details
Main Authors: Mathilde Maechler, Jörg Rösner, Iwona Wallach, Joerg R. P. Geiger, Claudia Spies, Agustin Liotta, Nikolaus Berndt
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
sevoflurane
neuron
metabolism
Online Access:https://www.mdpi.com/1422-0067/23/6/3037

Internet

https://www.mdpi.com/1422-0067/23/6/3037

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