Current Perspective on the Membrane-Damaging Action of Thermostable Direct Hemolysin, an Atypical Bacterial Pore-forming Toxin

Current Perspective on the Membrane-Damaging Action of Thermostable Direct Hemolysin, an Atypical Bacterial Pore-forming Toxin

Thermostable direct hemolysin (TDH) is the major virulence determinant of the gastroenteric bacterial pathogen Vibrio parahaemolyticus. TDH is a membrane-damaging pore-forming toxin (PFT). TDH shares remarkable structural similarity with the actinoporin family of eukaryotic PFTs produced by the sea...

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Bibliographic Details
Main Authors: Pratima Verma, Kausik Chattopadhyay
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
pore-forming toxin
thermostable direct hemolysin
membranes
actinoporins
oligomer
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.717147/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.717147/full

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