Twofold Mechanosensitivity Ensures Actin Cortex Reinforcement upon Peaks in Mechanical Tension

Abstract The actin cortex is an active polymer network underneath the plasma membrane at the periphery of mammalian cells. It is a major regulator of cell shape through the generation of active cortical tension. In addition, the cortex constitutes a mechanical shield that protects the cell during me...

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Bibliographic Details
Main Authors: Valentin Ruffine, Andreas Hartmann, Annika Frenzel, Michael Schlierf, Elisabeth Fischer‐Friedrich
Format: Article
Language:English
Published: Wiley-VCH 2023-12-01
Series:Advanced Physics Research
Subjects:
Online Access:https://doi.org/10.1002/apxr.202300046