Spectrophotometric Study of Charge-Transfer Complexes of Ruxolitinib with Chloranilic Acid and 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone: An Application to the Development of a Green and High-Throughput Microwell Method for Quantification of Ruxolitinib in Its Pharmaceutical Formulations

Spectrophotometric Study of Charge-Transfer Complexes of Ruxolitinib with Chloranilic Acid and 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone: An Application to the Development of a Green and High-Throughput Microwell Method for Quantification of Ruxolitinib in Its Pharmaceutical Formulations

Ruxolitinib (RUX) is a potent drug that has been approved by the Food and Drug Administration for the treatment of myelofibrosis, polycythemia vera, and graft-versus-host disease. This study describes the formation of colored charge-transfer complexes (CTCs) of RUX, an electron donor, with chloranil...

Full description

Bibliographic Details
Main Authors: Khalid A. Aljaber, Ibrahim A. Darwish, Abdullah M. Al-Hossaini
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
ruxolitinib
charge-transfer complex
microwell spectrophotometry
quality control
green and high-throughput approach
Online Access:https://www.mdpi.com/1420-3049/28/23/7877

Internet

https://www.mdpi.com/1420-3049/28/23/7877

Similar Items