Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits

Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits

Abstract Background There are increasing evidence that left ventricle diastolic dysfunction is the initial functional alteration in the diabetic myocardium. In this study, we hypothesized that alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function and structu...

Full description

Bibliographic Details
Main Authors: Xiaowei Zhang, Zhiwei Zhang, Yajuan Yang, Ya Suo, Ruimeng Liu, Jiuchun Qiu, Yungang Zhao, Ning Jiang, Changle Liu, Gary Tse, Guangping Li, Tong Liu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cardiovascular Diabetology
Subjects:
Dipeptidyl peptidase-4 inhibitors
Diabetic cardiomyopathy
Diabetes mellitus
Mitochondrial function
Mitochondrial biogenesis
Online Access:http://link.springer.com/article/10.1186/s12933-018-0803-z

Internet

http://link.springer.com/article/10.1186/s12933-018-0803-z

Similar Items