5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction
Abstract Blockade of N-methyl-D-aspartate receptors (NMDAR) is known to augment cortical serotonin 2A receptors (5-HT2ARs), which is implicated in psychosis. However, the pathways from NMDAR hypofunction to 5-HT2AR up-regulation are unclear. Here we addressed in mice whether genetic deletion of the...
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Nature Publishing Group
2022-04-01
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| श्रृंखला: | Translational Psychiatry |
| ऑनलाइन पहुंच: | https://doi.org/10.1038/s41398-022-01930-0 |