Molecular mechanisms involved in the inhibition of tumor cells proliferation exposed to elevated concentrations of the epidermal growth factor

Molecular mechanisms involved in the inhibition of tumor cells proliferation exposed to elevated concentrations of the epidermal growth factor

The EGF promotes inhibition of cell proliferation in vitro and in vivo models depending on its concentration, application schema and the type of tumor cells on which it acts. Our research hypothesis was based on the fact that the EGF varies the expression of genes involved in a negative regulation o...

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Bibliographic Details
Main Authors: Isabel A Guillén, Jorge Berlanga, Hanlet Camacho, María E Fernández-de-Cossio, Lincidio Pérez, Lidia I Novoa, Daniel O Palenzuela, Tamara Díaz, Gerardo E Guillén, Luis Herrera, Karelia Cosme, Laritza Gorovaya, Osmani Mendoza, Julio R Fernández, Julio A Ancizar, Jose Suarez, Ángela D Tuero, María E Ochagavía, Juan Roca, Jorge Gavilondo, Diana García del Barco, Jorge Martín
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
factor de crecimiento epidérmico
cáncer
expresión de genes
modelo animal
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522013000300008&lng=en&tlng=en

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http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522013000300008&lng=en&tlng=en

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