Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues
<p>Abstract</p> <p>Background</p> <p>The Nonsense-Mediated mRNA Decay (NMD) pathway detects and degrades mRNAs containing premature termination codons, thereby preventing the accumulation of potentially detrimental truncated proteins. Intertissue variation in the effici...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-12-01
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Series: | BMC Genetics |
Online Access: | http://www.biomedcentral.com/1471-2156/9/83 |